2019

London, UK

Day One
Wednesday March 21st, 2018

Day Two
Thursday March 22nd, 2018

08.00
Breakfast & Registration

09.00
Chairman’s Opening Remarks

  • Michael Holers Scoville Professor & Head, Division of Rheumatology, University of Colorado

Optimising Complement Efficacy Assessment & Diagnostics

09.30
Taking Complement Testing from Diagnostics to Drug Development: What is well suited for one may not do well for the other.

10.00
Panel: Developing a Roadmap for the Next Generation of Efficacy Assessment Techniques and Complement Diagnostics

  • Ashley Frazer-Abel Director, Exsera Biolabs
  • Tom Mollnes Professor of Immunology and Leader, Complement Research Group, University of Oslo
  • Michael Holers Scoville Professor & Head, Division of Rheumatology, University of Colorado

10.30
Speed Networking

11.00
Morning Refreshments

Expanding Complement Therapeutics Beyond Orphan Diseases

11.30
C5a/C5aR1 Signaling Alters Blood-Brain Barrier Integrity and Brain Function in Systemic Lupus Erythematosus

12.00
Inhibition of C5aR1 Alters Microglial Polarisation and Rescues Neuron Damage and Cognitive Loss in a Mouse Model of Alzheimer’s Disease

  • Andrea Tenner Professor of Molecular Biology & Biochemistry, University of California

12.30
Inhibition of C5a to Enhance the Efficacy of Cancer Immunotherapies

  • Kai Höhlig Director Preclinical Research, Aptarion Biotech AG

13.00
Lunch & Networking

14.00
Panel: Determining which Portion of the Complement Pathway is the Most Effective Intervention Point for Specific Diseases

  • Kai Höhlig Director Preclinical Research, Aptarion Biotech AG
  • Michael Holers Scoville Professor & Head, Division of Rheumatology, University of Colorado
  • Erik Hack CSO, Prothix

15.00
Complement-based Drug Development Round Tables

Synopsis

  1. Meeting Dosing and Efficacy Regulatory Requirements
  2. Emerging Indications for the Future of Complement Therapeutics
  3. Exploring the Micro- Landscape of Complement Related Compounds

16.00
Chairman’s Closing Remarks & Close of Day 1

  • Michael Holers Scoville Professor & Head, Division of Rheumatology, University of Colorado